Glycopyrrolate (glye-koe-PIR-oh-late)

Treats chronic obstructive pulmonary disease (COPD).

Brand Name(s):

When This Medicine Should Not Be Used:

How to Use This Medicine:

Capsule, Liquid

• Your doctor or other health caregiver should show you how to use this medicine. Use it at the same time every day. Do not use more medicine or use it more often than instructed.
• To use the Lonhala™ Magnair®:
  • Lonhala™vials should be used only with the Magnair® device. Do not swallow the liquid in the vial. Do not use the device with any other medicine.
  • Use this medicine at the same time each day, in the morning and evening.
  • Open the foil pouch and remove the 2 vials.
  • Separate the 2 vials and place one back in the pouch for the next treatment.
  • Check the liquid in the vial. It should be clear and colorless. Do not use it if it is discolored.
• To use the Seebri™ Neohaler®:
  • Seebri™capsules should be used only with the Neohaler® device. Do not swallow the capsule. Do not use the device with any other medicine.
  • Do not remove the capsule from the blister pack until you are ready to use it. Use the capsule right away once you have opened a blister pack.
  • Use a new inhaler with each refill of your medicine. Do not use the inhaler with any other medicine.
• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
• Missed dose:
  • Lonhala™ Magnair®: If you miss a dose, take your next dose at your usual time. Do not use 2 vials at a time. Do not use more than 2 vials in a day.
  • Seebri™ Neohaler®: Skip the missed dose and go back to your regular dosing schedule. Do not use extra medicine to make up for a missed dose.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. You may store the unused vials in the foil pouch until 7 days.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how glycopyrrolate works. Tell your doctor if you are using medicine to treat incontinence. Also tell your doctor if you take other medicine that can cause dry mouth or constipation (including aclidinium, ipratropium, tiotropium, or umeclidinium).

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, asthma, glaucoma, enlarged prostate, bladder problems, or trouble urinating. Tell your doctor if you are allergic to milk.
• This medicine may cause paradoxical bronchospasm (increased trouble breathing), which can be life-threatening.
• Do not use this medicine for a sudden COPD attack. Make sure you always have your rescue medicine with you to treat sudden symptoms. Tell your doctor right away if your condition gets worse or you need to use your other medicine more often than usual.
• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blurred vision, eye pain, seeing halos around objects
• Change in how much or how often you urinate, difficult or painful urination
• Increased trouble breathing

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088