Mirabegron (mir-a-BEG-ron)

Treats bladder problems, including neurogenic detrusor overactivity and symptoms of an overactive bladder.

Brand Name(s):

Myrbetriq

When This Medicine Should Not Be Used:

How to Use This Medicine:

Liquid, Long Acting Tablet

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. This medicine usually works within 8 weeks after you start taking it.
• Swallow the extended-release tablet whole. Do not crush, break, or chew it. Adults may take this medicine with or without food. Children should take it with food.
• Oral liquid:
  • It is best to take this medicine within 1 hour with food.
  • Shake the bottle well just before taking each dose.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
• Missed dose: If you miss a dose and it is less than 12 hours from your regular schedule, take the dose as soon as you can. If you miss a dose and it is more than 12 hours, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
• Throw away any unused oral liquid 28 days after first opening the bottle.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how mirabegron works. Tell your doctor if you are using desipramine, digoxin, flecainide, metoprolol, propafenone, thioridazine, or a blood thinner (including warfarin).

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, high blood pressure, or bladder outlet obstruction (trouble urinating or a weak urine stream).
• This medicine may cause the following problems:
  • High blood pressure
  • Urinary retention (trouble passing urine or not fully emptying the bladder) when used together with another medicine
  • Angioedema (severe swelling)
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Bloody or cloudy urine, lower back or side pain, difficult or painful urination
• Blurred vision, headache, fast, pounding, or uneven heartbeat, lightheadedness, dizziness

If you notice these less serious side effects, talk with your doctor:

• Constipation
• Dry mouth, sore throat

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088