Alvimopan (al-vi-MOE-pan)

Helps restore bowel function after bowel surgery.

Brand Name(s):

Entereg

When This Medicine Should Not Be Used:

How to Use This Medicine:

Capsule

• A nurse or other trained health professional will give you this medicine.
• This medicine is used only as part of a special program called Entereg® Access Support and Education (E.A.S.E.) in hospitalized patients. It is intended for short-term use only.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how alvimopan works. Tell your doctor if you took an opioid pain medicine (such as codeine, fentanyl, methadone, or morphine) within the past week.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or blocked bowels.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Constipation, passing gas, or diarrhea
• Decrease in how much or how often you urinate
• Dry mouth, increased thirst, muscle cramps, nausea, vomiting, or upset stomach
• Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

• Back pain

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088