Cosyntropin (koe-sin-TROE-pin)

Used as part of a medical test of the adrenal glands.

Brand Name(s):

Cortrosyn, Cosyntropin Novaplus

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• A nurse or other health provider will give you this medicine. This medicine is given as a shot into a muscle or into a vein.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not take spironolactone or glucocorticoids on the day of cosyntropin testing. Do not take medicines that contain estrogen 4 to 6 weeks before receiving this medicine.
• Some medicines can affect how cosyntropin works. Tell your doctor if you are using long-acting glucocorticoids.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blurred vision, dizziness, headache, nervousness, pounding in the ears
• Chest pain
• Fast, slow, pounding, or irregular heartbeat
• Rapid weight gain, swelling in your hands, ankles, or feet

If you notice these less serious side effects, talk with your doctor:

• Skin rash

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088