Repaglinide (re-PAG-li-nide)

Treats type 2 diabetes.

Brand Name(s):

Prandin

When This Medicine Should Not Be Used:

How to Use This Medicine:

Tablet

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
• Take this medicine before each meal, up to 4 times per day. You make take it up to 30 minutes before the meal.
• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. Do not take this medicine if you skip a meal.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not take gemfibrozil while you are using this medicine.
• Some medicines can affect how repaglinide works. Tell your doctor if you are using any of the following:
  • Albuterol, carbamazepine, clarithromycin, clonidine, clopidogrel, clozapine, cyclosporine, danazol, deferasirox, disopyramide, erythromycin, fluoxetine, guanethidine, isoniazid, itraconazole, ketoconazole, montelukast, niacin, octreotide, olanzapine, pentoxifylline, phenobarbital, pramlintide, reserpine, rifampin, somatropin, terbutaline, or trimethoprim
  • Birth control pill
  • Blood pressure medicine
  • Diuretic (water pill)
  • Insulin or other diabetes medicine
  • MAO inhibitor
  • Medicine to treat HIV infection
  • NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)
  • Phenothiazine medicine
  • Steroid medicine
  • Sulfa drug
  • Thyroid medicine

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or heart problems.
• This medicine may cause low blood sugar levels.
• This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blistering, peeling, red skin rash
• Seizures
• Shaking, trembling, sweating, fast or pounding heartbeat, faintness or lightheadedness, hunger, confusion

If you notice these less serious side effects, talk with your doctor:

• Cough, runny or stuffy nose, sore throat
• Weight gain

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088